As part of Office 365, OneDrive is the storage location for your files (replacing home directories on the server).  It is visible in Windows File Explorer as OneDrive - Domino Printing Sciences as below:

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(It should not be OneDrive - Personal as this indicates it has not been set up as a work/school account)






When you first sign in to OneDrive, it goes through a few steps and asks which folders you would like to backup.  By default, it automatically adds Desktop, Documents and Pictures folders. 


Backing up these folders means that should you have a hardware issue, you can log on to another device, sign in to OneDrive and access your files to continue working. 


If you want to change which folders are synced to OneDrive, please read below:



You can change the settings for OneDrive using the taskbar icon (or it maybe in the hidden icons, i.e. the upward pointing arrow).


Click on Help & Settings and select Settings from the menu that appears




You can then choose/review which folders to sync:



Uncheck any folder that you don't want to sync.


Click OK to apply the changes.